Endocrine Abstracts

A 37-year-old Caucasian female, pharmacist, referred to Diabetological center in February 2017. The main complaint was frequent urination.Medical history: She was diagnosed with T2DM at the age of 32 year. She was taking Metformin 850 mg twice daily. Her plasma glucose was 7.8 mmol/l at fasting; 10.8 mmol/l postprandial.Family history: Her father has elevated glucose levels also (up to 8 mmol/l before meal). Her moth...

A 40-year Caucasian female referred to Diabetes centre in November 2016. Her main complaints were 20 kg weight gain over the past 4 years, muscle weakness, high blood glucose readings, high blood pressure (up to 180/100 mmHg),menstrual irregularity.Medical historyShe was diagnosed with T2DM at the age of 39 year. She did not take any blood glucose lowering medication. Her blood glucose readings were: 12 mmol/l at fasting, 20 mmol/l...

Vologda is situated in the North-Western region of Russian Federation. It is mostly rural – about 30% of population lives in remoted villages. One can compare Vologdàs region with Greece – same amount of land area (approximately 140000 m2), but the population density is 10 times less (8 per km2 and 85 per km2 respectively). The Vologdàs region population is approximately 1151000, the amount of Diabetes patients is 42 000 (3,7% of overall population). The te...

BackgroundThe aim of the study was to evaluate urine steroid metabolomics by gas chromatography–mass spectrometry (GC–MS) for the adrenocortical carcinoma (ACC) metastases` biomarkers detection in patients after the surgery.Patients and methods33 postoperative ACC patients were examined before and after the surgery. The median age was 47 years (41–60). The Weiss score was more than 3 points acc...

Background: The aim of the study was to evaluate urine steroid profiles by gas chromatography–mass spectrometry (GC–MS) in patients with adrenocortical carcinoma (ACC) to assess therapy efficacy.Patients and Methods: 39 ACC patients were examined before and after treatment. The median age was 47 years (41–60). The Weiss score was no less than 4 points. 10 patients were disease-free in the early postoperative period (up to 12 months after s...